Fumonisins alter redox balance in Nile tilapia fingerlings

Fumonisins alter redox balance in Nile tilapia fingerlings

Fumonisins (FB) are secondary metabolites of Fusarium fungi, and their ingestion are associated with liver disease in different species of animals. This study tests the hypothesis that FB alter redox balance-related gene expression in Nile tilapia fingerlings. A total of 180 fish randomly distribute...

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Veröffentlicht in:Aquaculture 2021-01, Vol.530, p.735735, Article 735735
Hauptverfasser: Lala, Bruno, Santos, Carolina, Roldi, Gabriel, Roça, Roberto, Sampaio, Guilherme, Garcia, André, Garrido, Bruno, Ricci, Gleia, Refundini, Gislaine, Braccini, Graciela, Porto, Carla, Gasparino, Eliane, Claudino-Silva, Stefania Caroline
Format: Artikel
Sprache:eng
Schlagworte:
Fusarium moniliforme
Mycotoxin
Oreochromis niloticus
Oxidative stress
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Zusammenfassung:Fumonisins (FB) are secondary metabolites of Fusarium fungi, and their ingestion are associated with liver disease in different species of animals. This study tests the hypothesis that FB alter redox balance-related gene expression in Nile tilapia fingerlings. A total of 180 fish randomly distributed in four treatments were used: the control treatment (0.0), 20 (FB20), 40 (FB40) and 60 (FB60) mg/kg of FB, to evaluate Glutathione peroxidase (GPX) and heat shock protein (HSP70) mRNA expression in the liver. There was a significant effect of both treatment and exposure period for GPX, evidencing that the response is time-dependent. Similarly, there were exposure time (P 
ISSN:0044-8486
1873-5622
DOI:10.1016/j.aquaculture.2020.735735