Fusobacterium nucleatum bacteremia with pneumopathy in a patient receiving eculizumab: A case report

Fusobacterium nucleatum is a common oral commensal bacterium capable of severe invasive infections. We report a case of a diffuse bilateral pneumopathy with F. nucleatum-positive blood culture successfully treated by common antibiotics in a patient receiving eculizumab for a drug-induced thrombotic microangiopathy (TMA). It is the first described case of a severe F. nucleatum-associated infection in a patient undergoing terminal complement inhibitor therapy. We suggest providing preventive dental care before eculizumab initiation. •The field of application of eculizumab is currently spreading.•The pathogeny of Fusobacterium nucleatum depends on complement pathway activation.•Such a severe complication could be prevented by simple means.