Randomized control trial of intravenous acetaminophen for reduction of intrapartum maternal fever

Randomized control trial of intravenous acetaminophen for reduction of intrapartum maternal fever

Intravenous acetaminophen reaches a higher mean peak plasma concentration than oral acetaminophen in a shorter period of time. The favorable pharmacokinetics of intravenous acetaminophen may be beneficial for treating intrapartum maternal fever. The primary objective was to compare intravenous and o...

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Veröffentlicht in:American journal of obstetrics & gynecology MFM 2021-01, Vol.3 (1), p.100287, Article 100287
Hauptverfasser: Mehraban, Shadi, Nematian, Sepide, Mehraban, Shadan S., Petrucci, Samantha, Tricorico, Gabrielle, Parnas, Zarina, Shats, Lenny, Kanninen, Tomi, Moretti, Michael, Cabbad, Michael, Lakhi, Nisha
Format: Artikel
Sprache:eng
Schlagworte:
intrapartum fever
intravenous acetaminophen
oral acetaminophen
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Zusammenfassung:Intravenous acetaminophen reaches a higher mean peak plasma concentration than oral acetaminophen in a shorter period of time. The favorable pharmacokinetics of intravenous acetaminophen may be beneficial for treating intrapartum maternal fever. The primary objective was to compare intravenous and oral acetaminophen in time to defervescence (temperature
ISSN:2589-9333
2589-9333
DOI:10.1016/j.ajogmf.2020.100287