Drug-Associated Giant Cell Arteritis with Scalp Necrosis After Treatment with Pembrolizumab: a Case Report

Drug-Associated Giant Cell Arteritis with Scalp Necrosis After Treatment with Pembrolizumab: a Case Report

Giant cell arteritis (GCA) can be a rheumatologic complication of checkpoint inhibitor immunotherapy for the treatment of cancer. A rare and serious manifestation of GCA is scalp necrosis. We report a case of a patient who developed GCA and subsequent scalp necrosis after the initiation of immunothe...

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Veröffentlicht in:SN comprehensive clinical medicine 2022-01, Vol.4 (1), Article 37
Hauptverfasser: Dargham, Bassel Bou, Kang, Julianna, Gavin, Joshua, Nandan, Abhishek
Format: Artikel
Sprache:eng
Schlagworte:
Case Report
Medicine
Medicine & Public Health
Topical Collection on Medicine
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Zusammenfassung:Giant cell arteritis (GCA) can be a rheumatologic complication of checkpoint inhibitor immunotherapy for the treatment of cancer. A rare and serious manifestation of GCA is scalp necrosis. We report a case of a patient who developed GCA and subsequent scalp necrosis after the initiation of immunotherapy with the checkpoint inhibitor pembrolizumab for the treatment of metastatic melanoma. Such advanced cases of GCA may be increasingly recognized in the immunotherapy era of oncology.
ISSN:2523-8973
2523-8973
DOI:10.1007/s42399-022-01120-5