Oral Epithelial Dysplasia: A Review

Purpose of the Review Oral epithelial dysplasia is a common but poorly understand entity of the oral mucosa. Timely diagnosis and management of key to keeping this pre-malignant lesion from becoming a frank carcinoma. There is significant variability in diagnostic techniques and treatment options. This article will summarize the recent data on different diagnostic techniques and diagnostic adjuncts, it will then review the histopathology and treatment techniques. Recent Findings Numerous diagnostic methods including both chemical and optical techniques. There are no current universally accepted guidelines for diagnosis. The literature does not support one adjunct diagnostic technique over a traditional incisional biopsy. New evidence may support the future use of AI in the diagnosis of these lesions. There is also no consensus for definitive management of the dysplastic lesions. Current literature supports treatment of these lesions with a treatment based on the grade of the dysplasia. Summary Evidence supports the early diagnosis and definitive treatment of oral epithelial dysplasia to prevent the lesions from undergoing malignant transformation. There is considerable variance in both diagnosis and treatment in the literature.