Skin absorption potential of ZnO nanoparticles

In spite of widely use of zinc oxide (ZnO) nanoparticles (NPs) in cosmetic industry and in our daily lives, there are insufficient data on their potential of skin absorption. This study was conducted to investigate the potential of skin absorption induced by ZnO NPs, especially influences of the sur...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Toxicology and environmental health sciences 2011-12, Vol.3 (4), p.258-261
Hauptverfasser: Kim, Sun Yae, Jeong, Sang Hoon, Lee, Eun Young, Park, Yoon-Hee, Bae, Hyun Cheol, Jang, Yeon Sue, Maeng, Eun Ho, Kim, Meyoung-Kon, Son, Sang Wook
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In spite of widely use of zinc oxide (ZnO) nanoparticles (NPs) in cosmetic industry and in our daily lives, there are insufficient data on their potential of skin absorption. This study was conducted to investigate the potential of skin absorption induced by ZnO NPs, especially influences of the surface charge and different particle size. Assessment of potential of skin absorption was estimated using 3D EpiDerm™ model (EPI-200) as human skin equivalent model (HSEM). This study demonstrated no evidence of significant penetration of ZnO NPs into the HSEM after 24 h exposure.
ISSN:2005-9752
DOI:10.1007/s13530-011-0100-7