Correlation between weight loss and improvement of diabetes mellitus among obese type 2 diabetic patients

Correlation between weight loss and improvement of diabetes mellitus among obese type 2 diabetic patients

Objective To clarify the correlation between weight loss and the improvement of diabetes mellitus among obese patients with type 2 diabetes. Patients and methods One hundred and eighty untreated obese patients with type 2 diabetes with HOMA-R over 1.6 and HbA1c over 6.9 were enrolled to achieve weig...

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Veröffentlicht in:Diabetology International 2013-06, Vol.4 (2), p.132-137
Hauptverfasser: Harayama, Takuya, Yoshida, Toshihide, Yoshioka, Keiji, Kogure, Akinori, Sakai, Ryosuke, Yasui, Tetsuya, Kondo, Yuriko, Fukui, Michiaki, Hasegawa, Goji, Nakamura, Naoto
Format: Artikel
Sprache:eng
Schlagworte:
Body weight
Care and treatment
Dextrose
Diabetes
Diabetics
Endocrinology
Exercise therapy
Glucose
Glucose tolerance tests
Glycosylated hemoglobin
Medicine
Medicine & Public Health
Metabolic Diseases
Original Article
Type 2 diabetes
Weight loss
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Zusammenfassung:Objective To clarify the correlation between weight loss and the improvement of diabetes mellitus among obese patients with type 2 diabetes. Patients and methods One hundred and eighty untreated obese patients with type 2 diabetes with HOMA-R over 1.6 and HbA1c over 6.9 were enrolled to achieve weight reduction over 6 months with diet and exercise intervention. Six months after treatment, the subjects underwent a 75 g glucose tolerance test (OGTT), were diagnosed as the normal type, IGT type, or diabetic type, and potential factors for the normalization of glycemia were analyzed. Results Six-month treatment led to a significant reduction ( P  
ISSN:2190-1678
2190-1686
DOI:10.1007/s13340-013-0107-1