Neutrophil Counts to High-Density Lipoprotein Cholesterol Ratio: a Potential Predictor of Prognosis in Acute Ischemic Stroke Patients After Intravenous Thrombolysis

Neutrophil counts to high-density lipoprotein cholesterol ratio (NHR) is a relatively new and readily available indicator, and our study aimed to demonstrate its relationship with short-term prognosis after intravenous thrombolysis in acute ischemic stroke (AIS) patients and to make a simple compari...

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Veröffentlicht in:Neurotoxicity research 2020-12, Vol.38 (4), p.1001-1009
Hauptverfasser: Chen, Guangyong, Yang, Naiping, Ren, Junli, He, Yibo, Huang, Honghao, Hu, Xueting, Shen, Jiamin, Yang, Chenguang, Zeng, Tian, Hu, Jingyu, Tong, Wangyong, Yang, Dehao, Zhang, Yongyin
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Sprache:eng
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Zusammenfassung:Neutrophil counts to high-density lipoprotein cholesterol ratio (NHR) is a relatively new and readily available indicator, and our study aimed to demonstrate its relationship with short-term prognosis after intravenous thrombolysis in acute ischemic stroke (AIS) patients and to make a simple comparison with other prognostic indicators. We compared demographic and laboratory characteristics of AIS patients and healthy controls and grouped AIS patients according to NHR tertiles to contrast 3-month outcomes. Univariate and multivariate regression analyses were carried to further analyze the relationship between NHR and prognosis. Moreover, we compared the accuracy of several factors using receiver-operating characteristic curve. NHR levels of AIS patients were higher than those of healthy controls ( p  
ISSN:1029-8428
1476-3524
DOI:10.1007/s12640-020-00274-1