Synthesis and characterization of Trichloroisocyanouric acid functionalized mesoporous silica nanocomposite (SBA/TCCA) for the Acylation of Indole

Trichloroisocyanouric acid (TCCA)-functionalized mesoporous silica nanocomposites (SBA/ TCCA) were synthesized and characterized for the acylation of indole. The uniform incorporation of TCCA inside the SBA-15 matrix was confirmed by standard characterization techniques (PXRD, Adsorption studies, FT-IR, etc.). The catalytic activity studies of SBA/TCCA nanocomposites for acylation of indole showed high selectivity (60–90%) of the 3-acetyl indole compared to homogeneous TCCA (50%). The advantage of solid support for higher selectivity is also explained. Graphical Abstract Synthesis of SBA-15/TCCA nanocomposites by in situ functionalization of ordered SBA-15 and acylation of indole in the liquid phase for higher selectivity of 3-acylated product are reported.