Water mediated eco-friendly green protocol for one-pot synthesis of α-aminophosphonates at ambient conditions

Increasing environmental awareness and economic concerns have led to the consideration of highly efficient one-pot, three-component, green approaches for important organic synthons. We describe here a simple, elegant and high yielding protocol for the synthesis of α -aminophosphonates in totally sol...

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Veröffentlicht in:Journal of chemical sciences (Bangalore, India) India), 2014-05, Vol.126 (3), p.793-799
Hauptverfasser: MANDHA, SANTHOSH REDDY, ALLA, MANJULA, BOMMENA, VITTAL RAO
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Sprache:eng
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Zusammenfassung:Increasing environmental awareness and economic concerns have led to the consideration of highly efficient one-pot, three-component, green approaches for important organic synthons. We describe here a simple, elegant and high yielding protocol for the synthesis of α -aminophosphonates in totally solvent-free, catalyst-free conditions by reacting aldehydes, amines and trimethyl phosphite at ambient temperature. Graphical Abstract Here we describe a simple, elegant and high yielding protocol for the synthesis of α-aminophosphonates in solvent-free, catalyst-free conditions by reacting aldehydes, amines and trimethyl phosphite at ambient temperature.
ISSN:0974-3626
0973-7103
DOI:10.1007/s12039-014-0608-x