Lobectomy versus total thyroidectomy in children with post-Chernobyl thyroid cancer: a 15 year follow-up

In 1994, 21 Belarus children presenting papillary thyroid cancer (PTC) diagnosed after the Chernobyl disaster, and already submitted to subtotal surgery, underwent thyroid re-operation and post-operative radioiodine (131 I ) therapy. All were re-evaluated after a 15-year follow-up, to evaluate the r...

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Veröffentlicht in:Endocrine 2011-12, Vol.40 (3), p.432-436
Hauptverfasser: Antonelli, Alessandro, Fallahi, Poupak, Grosso, Mariano, Boni, Giuseppe, Minuto, Michele N., Miccoli, Paolo
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Sprache:eng
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Zusammenfassung:In 1994, 21 Belarus children presenting papillary thyroid cancer (PTC) diagnosed after the Chernobyl disaster, and already submitted to subtotal surgery, underwent thyroid re-operation and post-operative radioiodine (131 I ) therapy. All were re-evaluated after a 15-year follow-up, to evaluate the results of partial versus total thyroidectomy. Nineteen out of 21 children (mean age 9.2 years) had previously undergone a lobectomy. All cases underwent re-operation in 1994. Histology revealed a PTC in the residual lobe in three cases, three had lymph node metastases. After surgery, 20 patients underwent 131 I therapy. The post-131 I whole body scan was negative in seven cases, showed neck node metastases in five, lung metastases in three, multiple associated metastases in six. The follow-up was performed with rhTSH-stimulated serum thyroglobulin (Tg) evaluation and ultrasonography. Twenty patients showed Tg
ISSN:1355-008X
1559-0100
DOI:10.1007/s12020-011-9500-3