Comparison of Postprandial Oleic Acid, 9 c, 11 t CLA and 10 t, 12 c CLA Oxidation in Healthy Moderately Overweight Subjects

Few studies report the individual effect of 9 c, 11 t ‐ and 10 t, 12 c ‐CLA on human energy metabolism. We compared the postprandial oxidative metabolism of 9 c, 11 t ‐ and 10 t, 12 c ‐CLA and oleic acid (9 c ‐18:1) in 22 healthy moderately overweight volunteers. After 24 weeks supplementation with...

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Veröffentlicht in:Lipids 2010-11, Vol.45 (11), p.1047-1051
Hauptverfasser: Malpuech‐Brugère, Corinne, Mensink, Ronald P., Loreau, Olivier, Maret, Agnès, Fernie, Claire E., Lassel, Taous S., Chardigny, Jean Michel, Scrimgeour, Charlie M., Sébédio, Jean Louis, Beaufrère, Bernard
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Sprache:eng
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Zusammenfassung:Few studies report the individual effect of 9 c, 11 t ‐ and 10 t, 12 c ‐CLA on human energy metabolism. We compared the postprandial oxidative metabolism of 9 c, 11 t ‐ and 10 t, 12 c ‐CLA and oleic acid (9 c ‐18:1) in 22 healthy moderately overweight volunteers. After 24 weeks supplementation with 9 c, 11 t ‐ , 10 t, 12 c ‐CLA or 9 c ‐18:1 (3 g/day), subjects consumed a single oral bolus of the appropriate [1‐ 13 C]‐labeled fatty acid. 8 h post‐dose, cumulative oxidation was similar for 9 c ‐18:1 and 10 t, 12 c ( P = 0.66), but significantly higher for 9 c, 11 t ( P < 0.01).
ISSN:0024-4201
1558-9307
DOI:10.1007/s11745-010-3480-6