Pharmacotherapeutics of SARS-CoV-2 Infections

The COVID-19 pandemic has affected more than 38 million people world-wide by person to person transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therapeutic and preventative strategies for SARS-CoV-2 remains a significant challenge. Within the past several months, effe...

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Veröffentlicht in:Journal of neuroimmune pharmacology 2021-03, Vol.16 (1), p.12-37
Hauptverfasser: Kevadiya, Bhavesh D., Machhi, Jatin, Herskovitz, Jonathan, Oleynikov, Maxim D., Blomberg, Wilson R., Bajwa, Neha, Soni, Dhruvkumar, Das, Srijanee, Hasan, Mahmudul, Patel, Milankumar, Senan, Ahmed M., Gorantla, Santhi, McMillan, JoEllyn, Edagwa, Benson, Eisenberg, Robert, Gurumurthy, Channabasavaiah B., Reid, St Patrick M., Punyadeera, Chamindie, Chang, Linda, Gendelman, Howard E.
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Sprache:eng
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Zusammenfassung:The COVID-19 pandemic has affected more than 38 million people world-wide by person to person transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therapeutic and preventative strategies for SARS-CoV-2 remains a significant challenge. Within the past several months, effective treatment options have emerged and now include repurposed antivirals, corticosteroids and virus-specific antibodies. The latter has included convalescence plasma and monoclonal antibodies. Complete viral eradication will be achieved through an effective, safe and preventative vaccine. To now provide a comprehensive summary for each of the pharmacotherapeutics and preventative strategies being offered or soon to be developed for SARS-CoV-2. Graphical abstract
ISSN:1557-1890
1557-1904
1557-1904
DOI:10.1007/s11481-020-09968-x