Tareciliosides N–S: further cycloartane saponins from the leaves of Tarenna gracilipes, and cytotoxicity of saponins and triterpenes

Six cycloartane glycosides, named tareciliosides N–S, and a known iridoid glucoside, ixoroside, were isolated in further extensive studies on the 1-BuOH-soluble fraction of a MeOH extract of the leaves of Tarenna gracilipes. From the EtOAc-soluble fraction, three known triterpenes were isolated. The...

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Veröffentlicht in:Journal of natural medicines 2013-07, Vol.67 (3), p.503-511
Hauptverfasser: Zhao, Zhimin, Matsunami, Katsuyoshi, Otsuka, Hideaki, Shinzato, Takakazu, Takeda, Yoshio
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Sprache:eng
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Zusammenfassung:Six cycloartane glycosides, named tareciliosides N–S, and a known iridoid glucoside, ixoroside, were isolated in further extensive studies on the 1-BuOH-soluble fraction of a MeOH extract of the leaves of Tarenna gracilipes. From the EtOAc-soluble fraction, three known triterpenes were isolated. Their toxicities toward A549 and Leishmania major trypanosome protozoa were assayed. Triterpenes were selectively active in the two organisms.
ISSN:1340-3443
1861-0293
DOI:10.1007/s11418-012-0707-2