Two new flavonoids from Centella asiatica (Linn.)

Two new flavonoids from Centella asiatica (Linn.)

Two new flavonoids named castilliferol 1 and castillicetin 2 , as well as a known compound, isochlorogenic acid 3 , were isolated from the whole plant of Centella asiatica . Isolates 1 and 2 exhibited good antioxidant activity using 2,2-diphenyl-1-picryl hydrazyl radical solution with IC 50 values o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of natural medicines 2008-07, Vol.62 (3), p.369-373
Hauptverfasser: Subban, Ravi, Veerakumar, A., Manimaran, R., Hashim, K. M., Balachandran, Indira
Format: Artikel
Sprache:eng
Schlagworte:
Antioxidants - isolation & purification
Antioxidants - pharmacology
Biomedical and Life Sciences
Biomedicine
Biphenyl Compounds
Centella - chemistry
Chlorogenic Acid - analogs & derivatives
Chlorogenic Acid - isolation & purification
Complementary & Alternative Medicine
Flavonoids - isolation & purification
Flavonoids - pharmacology
Inhibitory Concentration 50
Magnetic Resonance Spectroscopy
Medicinal Chemistry
Natural Resource Letter
Pharmacology/Toxicology
Pharmacy
Picrates
Plant Extracts - chemistry
Plant Extracts - pharmacology
Plant Sciences
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Two new flavonoids named castilliferol 1 and castillicetin 2 , as well as a known compound, isochlorogenic acid 3 , were isolated from the whole plant of Centella asiatica . Isolates 1 and 2 exhibited good antioxidant activity using 2,2-diphenyl-1-picryl hydrazyl radical solution with IC 50 values of 23.10 and 13.30, respectively. The structures of these isolates were determined by analytical and spectral data, including 1-D and 2-D NMR spectra.
ISSN:1340-3443
1861-0293
DOI:10.1007/s11418-008-0229-0