Synthesis of 4,8-dioxa-1-azabicyclo[4.3.0]nonane-3,9-dione

A new bicyclic aziridino lactone 1 was synthesized from methyl 2,3-dibromopropionate and 2-amino-2-methylpropane-1,3-diol (AMPD). The reaction of compound 1 with benzyl chloroformate and subsequent treatment of the intermediate compound with 1,8-diazabicyclo[5.4.0]undec-7-ene gave a bicyclic lactone...

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Veröffentlicht in:	Russian chemical bulletin 2015-04, Vol.64 (4), p.960-961
Hauptverfasser:	Kostyanovskii, R. G., Krutius, O. N., Kadorkina, G. K., Chervin, I. I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Brief Communications Chemistry Chemistry and Materials Science Chemistry/Food Science Inorganic Chemistry Organic Chemistry
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	A new bicyclic aziridino lactone 1 was synthesized from methyl 2,3-dibromopropionate and 2-amino-2-methylpropane-1,3-diol (AMPD). The reaction of compound 1 with benzyl chloroformate and subsequent treatment of the intermediate compound with 1,8-diazabicyclo[5.4.0]undec-7-ene gave a bicyclic lactone, 4,8-dioxa-1-azabicyclo[4.3.0]nonane-3,9dione.
ISSN:	1066-5285 1573-9171
DOI:	10.1007/s11172-015-0963-x