Multi-component condensation of 4-hydroxy-6-methyl-1H-pyridin-2-one with carbonyl compounds and Meldrum’s acid

Multi-component condensation of 4-hydroxy-6-methyl-1H-pyridin-2-one with carbonyl compounds and Meldrum’s acid

A convenient method for the synthesis of earlier unknown substituted derivatives of 4-aryl-7-methyl-4,6-dihydro-3 H -pyrano[3,2- c ]pyridine-2,5-dione and ethyl 3-(4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)-3-arylpropionate was developed based on the multi-component condensation of 4-hydroxy-...

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Veröffentlicht in:Russian chemical bulletin 2014-02, Vol.63 (2), p.457-461
Hauptverfasser: Lichitskii, B. V., Osipov, A. O., Komogortsev, A. N., Dudinov, A. A., Krayushkin, M. M.
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Full Articles
Inorganic Chemistry
Organic Chemistry
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Zusammenfassung:A convenient method for the synthesis of earlier unknown substituted derivatives of 4-aryl-7-methyl-4,6-dihydro-3 H -pyrano[3,2- c ]pyridine-2,5-dione and ethyl 3-(4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)-3-arylpropionate was developed based on the multi-component condensation of 4-hydroxy-6-methyl-1 H -pyridin-2-one, Meldrum’s acid, and carbonyl compounds.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-014-0452-7