Synthesis of hydrophilic and lipophilic 4-arylcoumarin phosphates

Novel hydrophilic and lipophilic prodrugs, sodium 4-arylcoumarin dialkylphosphates and 4-arylcoumarin dioleyl phosphates, were synthesized by phosphorylation of 4-arylcoumarins with dialkylphosphites.

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Bibliographische Detailangaben
Veröffentlicht in:	Russian chemical bulletin 2011-10, Vol.60 (10), p.2003-2009
Hauptverfasser:	Selikhov, A. N., Malysheva, Y. B., Nyuchev, A. V., Sitnikov, N. S., Sharonova, E. A., Shavyrin, A. S., Combes, S., Fedorov, A. Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Chemistry and Materials Science Chemistry/Food Science Full Articles Inorganic Chemistry Organic Chemistry
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Novel hydrophilic and lipophilic prodrugs, sodium 4-arylcoumarin dialkylphosphates and 4-arylcoumarin dioleyl phosphates, were synthesized by phosphorylation of 4-arylcoumarins with dialkylphosphites.
ISSN:	1066-5285 1573-9171
DOI:	10.1007/s11172-011-0304-7