Synthesis of imidazolyl dithiocarbamates and their reactions with phenacyl bromides

The reactions of ethyl (5-carbamoyl-3 H -imidazol-4-yl)dithiocarbamate with phenacyl bromides afford the S-alkylation products as a mixture of E/Z -isomers, which undergo cyclization to 5-(2-oxo-4-arylthiazol-3-yl)-1 H -imidazole-4-carboxamides under the action of a base.

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Bibliographische Detailangaben
Veröffentlicht in:	Russian chemical bulletin 2011-05, Vol.60 (5), p.882-888
Hauptverfasser:	El’tsov, O. S., Mokrushin, V. S., Smirnova, M. V., Shafikov, M. Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Chemistry and Materials Science Chemistry/Food Science Full Articles Inorganic Chemistry Organic Chemistry
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The reactions of ethyl (5-carbamoyl-3 H -imidazol-4-yl)dithiocarbamate with phenacyl bromides afford the S-alkylation products as a mixture of E/Z -isomers, which undergo cyclization to 5-(2-oxo-4-arylthiazol-3-yl)-1 H -imidazole-4-carboxamides under the action of a base.
ISSN:	1066-5285 1573-9171
DOI:	10.1007/s11172-011-0138-3