Four-component reaction between cyanoacetamide, aryl aldehydes, and ethyl acetoacetate with ammonium carbonate

A new and efficient one-pot synthesis of dihydropyridones derivatives by four-component reaction between cyanoacetamide, aryl aldehydes, and ethyl acetoacetate with ammonium carbonate is described. The reactions were performed in water and ethanol under reflux conditions and afforded high yields of...

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Veröffentlicht in:Research on chemical intermediates 2015-02, Vol.41 (2), p.1001-1009
Hauptverfasser: Dehghan, Alimohammad, Singh, Sonia, Anary-Abbasinejad, Mohammad, Hassanabadi, Alireza
Format: Artikel
Sprache:eng
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Zusammenfassung:A new and efficient one-pot synthesis of dihydropyridones derivatives by four-component reaction between cyanoacetamide, aryl aldehydes, and ethyl acetoacetate with ammonium carbonate is described. The reactions were performed in water and ethanol under reflux conditions and afforded high yields of products. Graphical abstract
ISSN:0922-6168
1568-5675
DOI:10.1007/s11164-013-1250-9