HPLC and UPLC for Determining Drugs in Blood (A Review)

The application of HPLC and UPLC techniques to the analysis of drugs in blood plasma during bioequivalence investigations and clinical monitoring was reviewed. Various methods of sample preparation, chromatography, and detection were considered and their specific features were pointed out.

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Bibliographische Detailangaben
Veröffentlicht in:	Pharmaceutical chemistry journal 2013-07, Vol.47 (4), p.225-230
Hauptverfasser:	Medvedev, Yu. V., Ramenskaya, G. V., Shokhin, I. E., Yarushok, T. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Medicine Methods of Analysis and Process Control Organic Chemistry Pharmacology/Toxicology Pharmacy Structure of Chemical Compounds
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The application of HPLC and UPLC techniques to the analysis of drugs in blood plasma during bioequivalence investigations and clinical monitoring was reviewed. Various methods of sample preparation, chromatography, and detection were considered and their specific features were pointed out.
ISSN:	0091-150X 1573-9031
DOI:	10.1007/s11094-013-0933-2