Synthesis and anti-inflammatory activity of 3,1-benzoxazin-4(3H)-ones and N-acyl-5-iodoanthranilic acid amides

A series of new 3,1-benzoxazin-4(3H)-ones were synthesized and N-acyl-5-iodoanthranilic acid amides derived from them were obtained in a search for new biologically active derivatives of anthranilic acid. The anti-inflammatory activity of these compounds was evaluated. It is established that these classes of compounds are promising for further research on biologically active substances possessing anti-inflammatory activity.