Efficient synthesis of imidazole and pyrimidine derivatives

Efficient synthesis of imidazole and pyrimidine derivatives

A convenient and affordable synthetic pathway for obtaining new α-aminoamidines starting from aminonitriles is proposed. The α-aminoamidines obtained can be applied as substrates for further transformations and synthesis of imidazole- and pyrimidine-containing building blocks.

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Veröffentlicht in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2020-10, Vol.56 (10), p.1329-1334
Hauptverfasser: Kolomoitsev, Oleksii O., Gladkov, Eugene S., Kotlyar, Volodymyr M., Pedan, Polina I., Onipko, Oleksandr V., Buravov, Oleksandr V., Chebanov, Valentyn A.
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
Organic Chemistry
Pharmacy
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Zusammenfassung:A convenient and affordable synthetic pathway for obtaining new α-aminoamidines starting from aminonitriles is proposed. The α-aminoamidines obtained can be applied as substrates for further transformations and synthesis of imidazole- and pyrimidine-containing building blocks.
ISSN:0009-3122
1573-8353
DOI:10.1007/s10593-020-02818-x