Synthesis of 7-(3-piperidyl)-[1,6]naphthyridine and 7-(4-pipe-ridyl)[1,6]naphthyridine

Synthesis of 7-(3-piperidyl)-[1,6]naphthyridine and 7-(4-pipe-ridyl)[1,6]naphthyridine

7-(3-Piperidyl)- and 7-(4-piperidyl)[1,6]naphthyridines have been synthesized from 2-methylpyridine-3-carbaldehyde cyclohexylimine and the methylmethoxycarboxamides (Weinreb amides) of N-Boc- substituted nipecotic and isonipecotic acids.

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Bibliographische Detailangaben
Veröffentlicht in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2009-09, Vol.45 (9), p.1053-1057
Hauptverfasser: Kovalskiy, D. A, Perevalov, V. P
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
isoquinoline
naphthyridine
Organic Chemistry
Pharmacy
piperidine
Weinreb amide
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Zusammenfassung:7-(3-Piperidyl)- and 7-(4-piperidyl)[1,6]naphthyridines have been synthesized from 2-methylpyridine-3-carbaldehyde cyclohexylimine and the methylmethoxycarboxamides (Weinreb amides) of N-Boc- substituted nipecotic and isonipecotic acids.
ISSN:0009-3122
1573-8353
DOI:10.1007/s10593-009-0387-3