Synthesis and stereochemical structure of derivatives of 2-substituted 3-cyclohexenylamidoquinazolin-4-ones obtained from N'-cyclohexenecarbonyl-substituted hydrazides of 2-aminobenzoic acid and certain orthoesters

In the reaction of N'-cyclohexenecarbonyl-substituted hydrazides of 2-aminobenzoic acid with the trialkyl esters of formic, acetic, valeric, and benzoic acids at room temperature 3-cyclohexenylamidoquinazolin-4-ones with the respective substituent at the C-2 atom of the quinazoline ring were ob...

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Veröffentlicht in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2008-06, Vol.44 (6), p.722-728
Hauptverfasser: Zicane, D, Raviņa, I, Tetere, Z, Petrova, M, Liepinsh, E
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Sprache:eng
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Zusammenfassung:In the reaction of N'-cyclohexenecarbonyl-substituted hydrazides of 2-aminobenzoic acid with the trialkyl esters of formic, acetic, valeric, and benzoic acids at room temperature 3-cyclohexenylamidoquinazolin-4-ones with the respective substituent at the C-2 atom of the quinazoline ring were obtained. The spatial structure of the obtained compounds was studied by homonuclear and heteronuclear NMR.
ISSN:0009-3122
1573-8353
DOI:10.1007/s10593-008-0104-7