Hierarchical model for strain generalized streaming potential induced by the canalicular fluid flow of an osteon

A hierarchical model is developed to predict the streaming potential (SP) in the canaliculi of a loaded os teon. Canaliculi are assumed to run straight across the os teon annular cylinder wall, while disregarding the effect of lacuna. SP is generalized by the canalicular fluid flow. Ana lytical solu...

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Veröffentlicht in:Acta mechanica Sinica 2015-02, Vol.31 (1), p.112-121
Hauptverfasser: Wu, Xiao-Gang, Yu, Wei-Lun, Cen, Hai-Peng, Wang, Yan-Qin, Guo, Yuan, Chen, Wei-Yi
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Sprache:eng
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Zusammenfassung:A hierarchical model is developed to predict the streaming potential (SP) in the canaliculi of a loaded os teon. Canaliculi are assumed to run straight across the os teon annular cylinder wall, while disregarding the effect of lacuna. SP is generalized by the canalicular fluid flow. Ana lytical solutions are obtained for the canalicular fluid veloc ity, pressure, and SP. Results demonstrate that SP amplitude (SPA) is proportional to the pressure difference, strain am plitude, frequency, and strain rate amplitude. However, the key loading factor governing SP is the strain rate, which is a representative loading parameter under the specific phys iological state. Moreover, SPA is independent of canalicu lar length. This model links external loads to the canalicu lar fluid pressure, velocity, and SP, which can facilitate fur ther understanding of the mechanotransduction and electro mechanotransduction mechanisms of bones.
ISSN:0567-7718
1614-3116
DOI:10.1007/s10409-015-0002-z