CeCl3-promoted one-pot synthesis of multisubstituted bispyrano[2,3-c]pyrazole derivatives

A simple and efficient method was developed for the synthesis of multisubstituted bispyrano[2,3- c ]pyrazole derivatives via one-pot reaction of β-keto esters, hydrazine (or phenylhydrazine), terephthalaldehyde, and malononitrile in the presence of CeCl 3 ·7H 2 O (10 mol%) as a catalyst. This method provides the products in good yields after a simple workup procedure without further purification. Graphical abstract