Synthesis of a functionalized chromane derivative via a TiCl4-mediated cyclization reaction

The reaction of 1-methoxy-1,3-bis(silyloxy)-1,3-butadiene with N -salicylideneaniline results in the formation of a functionalized chromane derivative. Diffuse reflectance UV–Vis, ATR-IR, and Raman spectroscopic investigations showed that the reaction proceeds via formation of a titanium complex consisting of TiCl 4 and two molecules of the N -salicylideneaniline. In situ ATR-IR spectroscopy reveals that this 2:1 complex is responsible for the subsequent mode of interaction with the 1,3-bis(silyloxy)-1,3-butadiene and formation of the product. Graphical abstract