Synthesis of a succinate–dihydrotestosterone–dihydropyrimidine conjugate

Synthesis of a succinate–dihydrotestosterone–dihydropyrimidine conjugate

In this work a new steroid–dihydropyrimidine derivative was synthesized. The route involved preparation of a dihydrotestosterone–dihydropyrimidine derivative using dihydrotestosterone, benzaldehyde, and thiourea in the presence of hydrochloric acid, followed by esterification of the dihydrotestoster...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Monatshefte für Chemie 2010, Vol.141 (1), p.75-78
Hauptverfasser: Figueroa-Valverde, Lauro, Díaz-Cedillo, Francisco, Camacho-Luis, Abelardo
Format: Artikel
Sprache:eng
Schlagworte:
Analytical Chemistry
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Inorganic Chemistry
Organic Chemistry
Original Paper
Physical Chemistry
Theoretical and Computational Chemistry
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In this work a new steroid–dihydropyrimidine derivative was synthesized. The route involved preparation of a dihydrotestosterone–dihydropyrimidine derivative using dihydrotestosterone, benzaldehyde, and thiourea in the presence of hydrochloric acid, followed by esterification of the dihydrotestosterone–dihydropyrimidine derivative with succinic acid to form a succinate–dihydrotestosterone–dihydropyrimidine conjugate. Graphical Abstract
ISSN:0026-9247
1434-4475
DOI:10.1007/s00706-009-0223-6