Regioselective synthesis of 4-aryl-3,4-dihydro-1,3,5-triazino[2,1-a]isoindol-2-ones

The condensation of binucleophilic 3-amino-1-arylimino-1 H -isoindoles with bifunctional 1-chloro-benzylisocyanates occurs regioselectively resulting in 3,4-dihydro-1,3,5-triazino[2,1- a ]isoindol-2-one derivatives. The structures of the synthesized compounds were unambiguously established by N O E...

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Veröffentlicht in:Monatshefte für Chemie 2008-08, Vol.139 (8), p.939-943
Hauptverfasser: Biitseva, Angelina V., Hordiyenko, Olha V., Sukach, Volodymyr A., Vovk, Myhailo V., Pichugin, Konstantin A., Konovalova, Irina S., Shishkin, Oleg V.
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Sprache:eng
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Zusammenfassung:The condensation of binucleophilic 3-amino-1-arylimino-1 H -isoindoles with bifunctional 1-chloro-benzylisocyanates occurs regioselectively resulting in 3,4-dihydro-1,3,5-triazino[2,1- a ]isoindol-2-one derivatives. The structures of the synthesized compounds were unambiguously established by N O E experiments.
ISSN:0026-9247
1434-4475
DOI:10.1007/s00706-008-0860-1