Thiol derivatives of arylnaphthylmethane as novel anti-osteoporotic agents

(Mercaptophenyl)naphthylmethane derivatives were synthesized as novel estrogen receptor binding ligands. [4-(Methylsulfonyl)phenyl](naphth-1-yl)ketone shows a very promising activity towards osteoporosis.

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Veröffentlicht in:Monatshefte für Chemie 2008-10, Vol.139 (10), p.1269-1277
Hauptverfasser: Sangita, Kumar, Atul, Sharma, Shikha, Sengupta, Surojeet, Singh, Man Mohan, Ray, Suprabhat
Format: Artikel
Sprache:eng
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Zusammenfassung:(Mercaptophenyl)naphthylmethane derivatives were synthesized as novel estrogen receptor binding ligands. [4-(Methylsulfonyl)phenyl](naphth-1-yl)ketone shows a very promising activity towards osteoporosis.
ISSN:0026-9247
1434-4475
DOI:10.1007/s00706-007-0848-2