Complete genome sequence of a potential foot-and-mouth disease virus serotype O vaccine strain from Bangladesh

One of the six sublineages of the dominant O/ME-SA/Ind2001 lineage of foot-and-mouth disease virus (FMDV), Ind2001BD1 has already spread throughout 14 countries, including Bangladesh. Here, we report the complete genome sequence of the potential serotype O vaccine strain BAN/TA/Dh-301/2016, which ha...

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Veröffentlicht in:Archives of virology 2020-09, Vol.165 (9), p.2119-2122
Hauptverfasser: Al Amin, Md, Ali, Md. Rahmat, Alam, A. S. M. Rubayet Ul, Siddique, Mohammad Anwar, Rahaman, Md. Mizanur, Sultana, Munawar, Hossain, Md. Anwar
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Sprache:eng
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Zusammenfassung:One of the six sublineages of the dominant O/ME-SA/Ind2001 lineage of foot-and-mouth disease virus (FMDV), Ind2001BD1 has already spread throughout 14 countries, including Bangladesh. Here, we report the complete genome sequence of the potential serotype O vaccine strain BAN/TA/Dh-301/2016, which has been shown to provide protection against all the circulating serotype O viruses in Bangladesh. The viral genome is 8,211 nucleotide (nt) long with an open reading frame (ORF) of 6999 nt. The ORF is flanked by a 1098-nt-long 5′-UTR and a 114-nt-long 3′-UTR. Compared to the Indian FMDV serotype O vaccine strain O/India/R2/75 (AF204276), ten mutations were identified in the major antigenic sites of BAN/TA/Dh-301/2016 (MK088170.1).
ISSN:0304-8608
1432-8798
DOI:10.1007/s00705-020-04711-6