Cerebrospinal fluid 5-HIAA concentrations correlate with cardiac uptake of 123I-MIBG during myocardial scintigraphy in drug naïve Parkinson’s disease

We examined the correlations between cerebrospinal fluid (CSF) concentrations of homovanillic acid (HVA) and 5-hydroxyindole acetic acid (5-HIAA) and imaging assessment scores, using 123 I-Ioflupane SPECT and 123 I-MIBG myocardial scintigraphy in 23 drug naïve PD patients. The CSF 5-HIAA concentrati...

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Veröffentlicht in:Journal of Neural Transmission 2018-10, Vol.125 (10), p.1511-1514
Hauptverfasser: Murakami, Hidetomo, Yamamoto, Ken, Yasumoto, Taro, Kimura, Atsushi, Sakae, Yoshiki, Nomoto, Shohei, Kubota, Satomi, Watanabe, Daishi, Watanabe, Keiko, Saito, Yu, Yano, Satoshi, Ono, Kenjiro
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Sprache:eng
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Zusammenfassung:We examined the correlations between cerebrospinal fluid (CSF) concentrations of homovanillic acid (HVA) and 5-hydroxyindole acetic acid (5-HIAA) and imaging assessment scores, using 123 I-Ioflupane SPECT and 123 I-MIBG myocardial scintigraphy in 23 drug naïve PD patients. The CSF 5-HIAA concentration correlated with the H/M ratio of the delayed image ( r  = 0.458, p  
ISSN:0300-9564
1435-1463
DOI:10.1007/s00702-018-1917-x