Processability and biodegradability of polylactic acid nasal implants

In the current study, we produce a biodegradable scaffold used as an absorbable nasal implant by using polylactic acid (PLA). A new design for the biodegradable implant was introduced, and produced via insert injection molding. A metal part was inserted into a mold for the processing. A three-dimensional numerical analysis based on the finite element methods was employed to predict melt front advancement and optimize process condition. Two kinds of samples with different lengths were manufactured and compared in terms of the rheological behavior and warpage deformation. The change of density in the injection molded part was simulated, and the degree of biodegradation was evaluated with respect to time.