A Meta-analysis of TAE/TACE Versus Emergency Surgery in the Treatment of Ruptured HCC

Objectives To evaluate the efficacy and safety of TAE/TACE versus emergency surgery (ES) for spontaneous rupture of HCC (rHCC). Methods Eight databases (Web of Science, Pubmed, Embase, Cochrane Library, ClinicalTrial.gov, Wanfang, CNKI and VIP) were searched to obtain all related literature from the...

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Veröffentlicht in:	Cardiovascular and interventional radiology 2020-09, Vol.43 (9), p.1263-1276
Hauptverfasser:	Xu, Xinjian, Chen, Changsheng, Liu, Qiang, Huang, Xiangzhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Hepatocellular - blood supply Carcinoma, Hepatocellular - therapy Cardiac & Cardiovascular Systems Cardiology Cardiovascular System & Cardiology Chemoembolization, Therapeutic Complications Embolization Emergency medical care Hemostasis Hemostatics Hepatectomy - methods Humans Imaging Interventional Oncology Life Sciences & Biomedicine Liver Neoplasms - blood supply Liver Neoplasms - therapy Medical prognosis Medicine Medicine & Public Health Meta-analysis Mortality Nuclear Medicine Radiology Radiology, Nuclear Medicine & Medical Imaging Review Rupture, Spontaneous Science & Technology Subgroups Surgery Survival Treatment Outcome Ultrasound
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Zusammenfassung:	Objectives To evaluate the efficacy and safety of TAE/TACE versus emergency surgery (ES) for spontaneous rupture of HCC (rHCC). Methods Eight databases (Web of Science, Pubmed, Embase, Cochrane Library, ClinicalTrial.gov, Wanfang, CNKI and VIP) were searched to obtain all related literature from the inception dates to October 2019. Subgroup analyses based on the kind of study design and kind of embolization were conducted. Results Twenty-one studies comparing TAE/TACE with ES were eligible. A total of 974 rHCC participants (485 participants treated with TACE/TAE and 489 participants treated with ES) were included in the present meta-analysis. TAE/TACE group was associated with lower risk of complications (OR = 0.36; 95% CI, 0.22–0.57; P
ISSN:	0174-1551 1432-086X
DOI:	10.1007/s00270-020-02514-5