Synthesis and antimicrobial activity of pyrazolyl benzoxazoles, benzothiazoles and benzimidazoles

Synthesis and antimicrobial activity of pyrazolyl benzoxazoles, benzothiazoles and benzimidazoles

A new class of amido-linked pyrazolyl benzoxazoles, benzothiazoles and benzimidazoles was prepared and studied for their antimicrobial activity. The chloro-substituted pyrazolyl benzothiazole is the potent antibacterial agent against Bacillus subtilis and chloro-substituted pyrazolyl benzimidazole i...

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Veröffentlicht in:Medicinal chemistry research 2015-03, Vol.24 (3), p.970-979
Hauptverfasser: Reddy, Lingaladinne Mallikarjuna, Prakash, Talapuru Bhanu, Padmaja, Adivireddy, Padmavathi, Venkatapuram
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry
Biomedical and Life Sciences
Biomedicine
Cell Biology
Original Research
Pharmacology/Toxicology
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Zusammenfassung:A new class of amido-linked pyrazolyl benzoxazoles, benzothiazoles and benzimidazoles was prepared and studied for their antimicrobial activity. The chloro-substituted pyrazolyl benzothiazole is the potent antibacterial agent against Bacillus subtilis and chloro-substituted pyrazolyl benzimidazole is the potent antifungal agent against Aspergillus niger .
ISSN:1054-2523
1554-8120
DOI:10.1007/s00044-014-1180-0