Synthesis and antioxidant activity of pyrazolyl-oxazolines/thiazolines and isoxazolyl-oxazolines/thiazolines

A new class of pyrazolyl/isoxazolyl-oxazolines and thiazolines were synthesized from E -arylsulfonylethenesulfonylacetic acid methyl ester and tested for antioxidant activity. Among the tested compounds, 14b exhibited excellent antioxidant activity when compared with the standard ascorbic acid.

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Veröffentlicht in:Medicinal chemistry research 2014-03, Vol.23 (3), p.1084-1098
Hauptverfasser: Padmaja, Adivireddy, Rajasekhar, Chittoor, Durgamma, Suram, Venkatesh, Bhumireddy Chinnachennaiahgari, Padmavathi, Venkatapuram
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Sprache:eng
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Zusammenfassung:A new class of pyrazolyl/isoxazolyl-oxazolines and thiazolines were synthesized from E -arylsulfonylethenesulfonylacetic acid methyl ester and tested for antioxidant activity. Among the tested compounds, 14b exhibited excellent antioxidant activity when compared with the standard ascorbic acid.
ISSN:1054-2523
1554-8120
DOI:10.1007/s00044-013-0688-z