Recent advances in liposome formulations for breast cancer therapeutics

Among many nanoparticle-based delivery platforms, liposomes have been particularly successful with many formulations passed into clinical applications. They are well-established and effective gene and/or drug delivery systems, widely used in cancer therapy including breast cancer. In this review we...

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Veröffentlicht in:Cellular and molecular life sciences : CMLS 2021-07, Vol.78 (13), p.5225-5243
Hauptverfasser: Yang, Biyao, Song, Bo-ping, Shankar, Shaina, Guller, Anna, Deng, Wei
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Sprache:eng
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Zusammenfassung:Among many nanoparticle-based delivery platforms, liposomes have been particularly successful with many formulations passed into clinical applications. They are well-established and effective gene and/or drug delivery systems, widely used in cancer therapy including breast cancer. In this review we discuss liposome design with the targeting feature and triggering functions. We also summarise the recent progress (since 2014) in liposome-based therapeutics for breast cancer including chemotherapy and gene therapy. We finally identify some challenges on the liposome technology development for the future clinical translation.
ISSN:1420-682X
1420-9071
DOI:10.1007/s00018-021-03850-6