Improvement of drug absorption through enhancers

The application of enhancers for improvement of drug absorption via the nasal, transdermal and rectal route are outlined. The importance of the relation between the time course of the enhancing effect and the desired plasma - concentration - time profile of the drug is stressed as well as the need t...

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Veröffentlicht in:	European journal of drug metabolism and pharmacokinetics 1990-04, Vol.15 (2), p.155-157
Hauptverfasser:	DE BOER, A. G, VAN HOOGDALEM, E. J, BREIMER, D. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Animals Biological and medical sciences Chemistry, Pharmaceutical - methods Drug Synergism General pharmacology Medical sciences Pharmacokinetics Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The application of enhancers for improvement of drug absorption via the nasal, transdermal and rectal route are outlined. The importance of the relation between the time course of the enhancing effect and the desired plasma - concentration - time profile of the drug is stressed as well as the need to pay more attention to the safety aspects of absorption enhancers.
ISSN:	0378-7966 2107-0180
DOI:	10.1007/BF03190198