Modifying effect of iron on lead-induced clastogenicity in mouse bone marrow cells
Essential trace elements such as iron (Fe) are known to interact with nonessential metals like lead (Pb), influencing its metabolism. Ferric chloride and lead nitrate were administered intraperitoneally to Swiss albino mice Mus musculus singly and successively, with or without a time gap of 1 h, to...
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| Veröffentlicht in: | Biological trace element research 1992-09, Vol.34 (3), p.279-286 |
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| container_title | Biological trace element research |
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| creator | HAIMANTI DHIR SHARMA, A TALUKDER, G |
| description | Essential trace elements such as iron (Fe) are known to interact with nonessential metals like lead (Pb), influencing its metabolism. Ferric chloride and lead nitrate were administered intraperitoneally to Swiss albino mice Mus musculus singly and successively, with or without a time gap of 1 h, to study the degree of protection, if any, afforded by iron against the clastogenic effects induced by Pb in bone marrow cells. A decrease in the frequency of lead-induced chromosomal aberrations was observed when Fe was given together with or prior to Pb administration. |
| doi_str_mv | 10.1007/BF02783683 |
| format | Article |
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Ferric chloride and lead nitrate were administered intraperitoneally to Swiss albino mice Mus musculus singly and successively, with or without a time gap of 1 h, to study the degree of protection, if any, afforded by iron against the clastogenic effects induced by Pb in bone marrow cells. A decrease in the frequency of lead-induced chromosomal aberrations was observed when Fe was given together with or prior to Pb administration.</description><identifier>ISSN: 0163-4984</identifier><identifier>EISSN: 1559-0720</identifier><identifier>DOI: 10.1007/BF02783683</identifier><identifier>PMID: 1384618</identifier><identifier>CODEN: BTERDG</identifier><language>eng</language><publisher>Heidelberg: Springer</publisher><subject>Animals ; Biological and medical sciences ; Bone Marrow - drug effects ; Bone Marrow Cells ; Chemical and industrial products toxicology. Toxic occupational diseases ; Chlorides ; Chromosome Aberrations ; Drug Interactions ; Ferric Compounds - administration & dosage ; Ferric Compounds - pharmacology ; Injections, Intraperitoneal ; Lead - administration & dosage ; Lead - toxicity ; Medical sciences ; Metals and various inorganic compounds ; Mice ; Nitrates - administration & dosage ; Nitrates - toxicity ; Toxicology</subject><ispartof>Biological trace element research, 1992-09, Vol.34 (3), p.279-286</ispartof><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c270t-ef20abf00a17ed375b3893c2ed6ea7761d99f766b63cce75911598e4d91d95463</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4456464$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1384618$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HAIMANTI DHIR</creatorcontrib><creatorcontrib>SHARMA, A</creatorcontrib><creatorcontrib>TALUKDER, G</creatorcontrib><title>Modifying effect of iron on lead-induced clastogenicity in mouse bone marrow cells</title><title>Biological trace element research</title><addtitle>Biol Trace Elem Res</addtitle><description>Essential trace elements such as iron (Fe) are known to interact with nonessential metals like lead (Pb), influencing its metabolism. Ferric chloride and lead nitrate were administered intraperitoneally to Swiss albino mice Mus musculus singly and successively, with or without a time gap of 1 h, to study the degree of protection, if any, afforded by iron against the clastogenic effects induced by Pb in bone marrow cells. A decrease in the frequency of lead-induced chromosomal aberrations was observed when Fe was given together with or prior to Pb administration.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Bone Marrow - drug effects</subject><subject>Bone Marrow Cells</subject><subject>Chemical and industrial products toxicology. Toxic occupational diseases</subject><subject>Chlorides</subject><subject>Chromosome Aberrations</subject><subject>Drug Interactions</subject><subject>Ferric Compounds - administration & dosage</subject><subject>Ferric Compounds - pharmacology</subject><subject>Injections, Intraperitoneal</subject><subject>Lead - administration & dosage</subject><subject>Lead - toxicity</subject><subject>Medical sciences</subject><subject>Metals and various inorganic compounds</subject><subject>Mice</subject><subject>Nitrates - administration & dosage</subject><subject>Nitrates - toxicity</subject><subject>Toxicology</subject><issn>0163-4984</issn><issn>1559-0720</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1LAzEQQIMotVYv3oUcPAmryeb7qMWqUBFEz0s2mZTINimbLdJ_70qLwsAc3mMYHkKXlNxSQtTdw4LUSjOp2RGaUiFMRVRNjtGUUMkqbjQ_RWelfBFCVW3YBE0o01xSPUXvr9nHsItphSEEcAPOAcc-JzxOB9ZXMfmtA49dZ8uQV5Cii8MOx4TXeVsAtzkBXtu-z9_YQdeVc3QSbFfg4rBn6HPx-DF_rpZvTy_z-2XlakWGCkJNbBsIsVSBZ0q0TBvmavASrFKSemOCkrKVzDlQwlAqjAbuzUgEl2yGbvZ3XZ9L6SE0mz6Oj-waSprfLs1_l1G-2subbbsG_6_uQ4z8-sBtcbYLvU0ulj-NcyG55OwHVK1pww</recordid><startdate>19920901</startdate><enddate>19920901</enddate><creator>HAIMANTI DHIR</creator><creator>SHARMA, A</creator><creator>TALUKDER, G</creator><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19920901</creationdate><title>Modifying effect of iron on lead-induced clastogenicity in mouse bone marrow cells</title><author>HAIMANTI DHIR ; SHARMA, A ; TALUKDER, G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c270t-ef20abf00a17ed375b3893c2ed6ea7761d99f766b63cce75911598e4d91d95463</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Bone Marrow - drug effects</topic><topic>Bone Marrow Cells</topic><topic>Chemical and industrial products toxicology. 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Ferric chloride and lead nitrate were administered intraperitoneally to Swiss albino mice Mus musculus singly and successively, with or without a time gap of 1 h, to study the degree of protection, if any, afforded by iron against the clastogenic effects induced by Pb in bone marrow cells. A decrease in the frequency of lead-induced chromosomal aberrations was observed when Fe was given together with or prior to Pb administration.</abstract><cop>Heidelberg</cop><pub>Springer</pub><pmid>1384618</pmid><doi>10.1007/BF02783683</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0163-4984 |
| ispartof | Biological trace element research, 1992-09, Vol.34 (3), p.279-286 |
| issn | 0163-4984 1559-0720 |
| language | eng |
| recordid | cdi_crossref_primary_10_1007_BF02783683 |
| source | MEDLINE; SpringerNature Complete Journals |
| subjects | Animals Biological and medical sciences Bone Marrow - drug effects Bone Marrow Cells Chemical and industrial products toxicology. Toxic occupational diseases Chlorides Chromosome Aberrations Drug Interactions Ferric Compounds - administration & dosage Ferric Compounds - pharmacology Injections, Intraperitoneal Lead - administration & dosage Lead - toxicity Medical sciences Metals and various inorganic compounds Mice Nitrates - administration & dosage Nitrates - toxicity Toxicology |
| title | Modifying effect of iron on lead-induced clastogenicity in mouse bone marrow cells |
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