Digitalis toxicity in infants and children
There is a narrow difference between the therapeutic and toxic ranges of cardiac glycosides. The availability in the past decade of radioimmunoassays for accurate measurement of these glycosides has resulted in an improved understanding of their pharmacokinetics and clinical use. Despite these advan...
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| Veröffentlicht in: | Pediatric cardiology 1984-04, Vol.5 (2), p.131-148 |
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| container_end_page | 148 |
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| container_issue | 2 |
| container_start_page | 131 |
| container_title | Pediatric cardiology |
| container_volume | 5 |
| creator | Hastreiter, A R van der Horst, R L Chow-Tung, E |
| description | There is a narrow difference between the therapeutic and toxic ranges of cardiac glycosides. The availability in the past decade of radioimmunoassays for accurate measurement of these glycosides has resulted in an improved understanding of their pharmacokinetics and clinical use. Despite these advances, however, digitalis toxicity is still a common problem in infants and children. |
| doi_str_mv | 10.1007/BF02424966 |
| format | Article |
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The availability in the past decade of radioimmunoassays for accurate measurement of these glycosides has resulted in an improved understanding of their pharmacokinetics and clinical use. Despite these advances, however, digitalis toxicity is still a common problem in infants and children.</description><identifier>ISSN: 0172-0643</identifier><identifier>EISSN: 1432-1971</identifier><identifier>DOI: 10.1007/BF02424966</identifier><identifier>PMID: 6473124</identifier><language>eng</language><publisher>United States</publisher><subject>Anti-Arrhythmia Agents - therapeutic use ; Antibodies - analysis ; Arrhythmias, Cardiac - chemically induced ; Arrhythmias, Cardiac - drug therapy ; Brain - drug effects ; Child ; Child, Preschool ; Combined Modality Therapy ; Digitalis Glycosides - poisoning ; Digoxin - blood ; Digoxin - immunology ; Digoxin - poisoning ; Dose-Response Relationship, Drug ; Heart Conduction System - drug effects ; Hemodynamics - drug effects ; Humans ; Immunoglobulin Fab Fragments - analysis ; Infant</subject><ispartof>Pediatric cardiology, 1984-04, Vol.5 (2), p.131-148</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c282t-8cb646bf372a86b0617afc61f690ee1814c537653205c468cb05a71fab8a31db3</citedby><cites>FETCH-LOGICAL-c282t-8cb646bf372a86b0617afc61f690ee1814c537653205c468cb05a71fab8a31db3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6473124$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hastreiter, A R</creatorcontrib><creatorcontrib>van der Horst, R L</creatorcontrib><creatorcontrib>Chow-Tung, E</creatorcontrib><title>Digitalis toxicity in infants and children</title><title>Pediatric cardiology</title><addtitle>Pediatr Cardiol</addtitle><description>There is a narrow difference between the therapeutic and toxic ranges of cardiac glycosides. The availability in the past decade of radioimmunoassays for accurate measurement of these glycosides has resulted in an improved understanding of their pharmacokinetics and clinical use. Despite these advances, however, digitalis toxicity is still a common problem in infants and children.</description><subject>Anti-Arrhythmia Agents - therapeutic use</subject><subject>Antibodies - analysis</subject><subject>Arrhythmias, Cardiac - chemically induced</subject><subject>Arrhythmias, Cardiac - drug therapy</subject><subject>Brain - drug effects</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Combined Modality Therapy</subject><subject>Digitalis Glycosides - poisoning</subject><subject>Digoxin - blood</subject><subject>Digoxin - immunology</subject><subject>Digoxin - poisoning</subject><subject>Dose-Response Relationship, Drug</subject><subject>Heart Conduction System - drug effects</subject><subject>Hemodynamics - drug effects</subject><subject>Humans</subject><subject>Immunoglobulin Fab Fragments - analysis</subject><subject>Infant</subject><issn>0172-0643</issn><issn>1432-1971</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFz8FLwzAUx_EgyuymF-9Cz4Pqe0n6kh51OicMvOi5JGmika4bTQX331vZUHjwLh9-8GXsCuEGAdTt_RK45LIiOmEZSsELrBSesgxQ8QJIinM2TekTADTocsImJJVALjM2f4jvcTBtTPmw_Y4uDvs8duMF0w0pN12Tu4_YNr3vLthZMG3yl8c_Y2_Lx9fFqli_PD0v7taF45oPhXaWJNkgFDeaLBAqExxhoAq8R43SlUJRKTiUTtLIoTQKg7HaCGysmLH5Ydf125R6H-pdHzem39cI9W9v_d874usD3n3ZjW_-6DFQ_ADqHk4f</recordid><startdate>198404</startdate><enddate>198404</enddate><creator>Hastreiter, A R</creator><creator>van der Horst, R L</creator><creator>Chow-Tung, E</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>198404</creationdate><title>Digitalis toxicity in infants and children</title><author>Hastreiter, A R ; van der Horst, R L ; Chow-Tung, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c282t-8cb646bf372a86b0617afc61f690ee1814c537653205c468cb05a71fab8a31db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Anti-Arrhythmia Agents - therapeutic use</topic><topic>Antibodies - analysis</topic><topic>Arrhythmias, Cardiac - chemically induced</topic><topic>Arrhythmias, Cardiac - drug therapy</topic><topic>Brain - drug effects</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Combined Modality Therapy</topic><topic>Digitalis Glycosides - poisoning</topic><topic>Digoxin - blood</topic><topic>Digoxin - immunology</topic><topic>Digoxin - poisoning</topic><topic>Dose-Response Relationship, Drug</topic><topic>Heart Conduction System - drug effects</topic><topic>Hemodynamics - drug effects</topic><topic>Humans</topic><topic>Immunoglobulin Fab Fragments - analysis</topic><topic>Infant</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hastreiter, A R</creatorcontrib><creatorcontrib>van der Horst, R L</creatorcontrib><creatorcontrib>Chow-Tung, E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Pediatric cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hastreiter, A R</au><au>van der Horst, R L</au><au>Chow-Tung, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Digitalis toxicity in infants and children</atitle><jtitle>Pediatric cardiology</jtitle><addtitle>Pediatr Cardiol</addtitle><date>1984-04</date><risdate>1984</risdate><volume>5</volume><issue>2</issue><spage>131</spage><epage>148</epage><pages>131-148</pages><issn>0172-0643</issn><eissn>1432-1971</eissn><abstract>There is a narrow difference between the therapeutic and toxic ranges of cardiac glycosides. The availability in the past decade of radioimmunoassays for accurate measurement of these glycosides has resulted in an improved understanding of their pharmacokinetics and clinical use. Despite these advances, however, digitalis toxicity is still a common problem in infants and children.</abstract><cop>United States</cop><pmid>6473124</pmid><doi>10.1007/BF02424966</doi><tpages>18</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0172-0643 |
| ispartof | Pediatric cardiology, 1984-04, Vol.5 (2), p.131-148 |
| issn | 0172-0643 1432-1971 |
| language | eng |
| recordid | cdi_crossref_primary_10_1007_BF02424966 |
| source | MEDLINE; SpringerNature Journals |
| subjects | Anti-Arrhythmia Agents - therapeutic use Antibodies - analysis Arrhythmias, Cardiac - chemically induced Arrhythmias, Cardiac - drug therapy Brain - drug effects Child Child, Preschool Combined Modality Therapy Digitalis Glycosides - poisoning Digoxin - blood Digoxin - immunology Digoxin - poisoning Dose-Response Relationship, Drug Heart Conduction System - drug effects Hemodynamics - drug effects Humans Immunoglobulin Fab Fragments - analysis Infant |
| title | Digitalis toxicity in infants and children |
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