Digitalis toxicity in infants and children

Digitalis toxicity in infants and children

There is a narrow difference between the therapeutic and toxic ranges of cardiac glycosides. The availability in the past decade of radioimmunoassays for accurate measurement of these glycosides has resulted in an improved understanding of their pharmacokinetics and clinical use. Despite these advan...

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Veröffentlicht in:Pediatric cardiology 1984-04, Vol.5 (2), p.131-148
Hauptverfasser: Hastreiter, A R, van der Horst, R L, Chow-Tung, E
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Arrhythmia Agents - therapeutic use
Antibodies - analysis
Arrhythmias, Cardiac - chemically induced
Arrhythmias, Cardiac - drug therapy
Brain - drug effects
Child
Child, Preschool
Combined Modality Therapy
Digitalis Glycosides - poisoning
Digoxin - blood
Digoxin - immunology
Digoxin - poisoning
Dose-Response Relationship, Drug
Heart Conduction System - drug effects
Hemodynamics - drug effects
Humans
Immunoglobulin Fab Fragments - analysis
Infant
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Beschreibung
Zusammenfassung:There is a narrow difference between the therapeutic and toxic ranges of cardiac glycosides. The availability in the past decade of radioimmunoassays for accurate measurement of these glycosides has resulted in an improved understanding of their pharmacokinetics and clinical use. Despite these advances, however, digitalis toxicity is still a common problem in infants and children.
ISSN:0172-0643
1432-1971
DOI:10.1007/BF02424966