Influence on erythropoietin levels of treatment with cisplatinum-endoxan

Erythropoietin levels have been determined in 24 patients with different gynecologic malignancies, who were treated with cisplatinum and endoxan. A statistically highly significant decrease was demonstrated 2 h after starting treatment with a further significant decrease at 6 h. After 12 h the eryth...

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Veröffentlicht in:Archives of gynecology and obstetrics 1992-09, Vol.252 (1), p.49-53
Hauptverfasser: Lechner, W, Artner-Dworzak, E, Sölder, E, Sachsenmaier, M, Kölle, D, Moncayo, H, Reitsamer, R
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container_end_page 53
container_issue 1
container_start_page 49
container_title Archives of gynecology and obstetrics
container_volume 252
creator Lechner, W
Artner-Dworzak, E
Sölder, E
Sachsenmaier, M
Kölle, D
Moncayo, H
Reitsamer, R
description Erythropoietin levels have been determined in 24 patients with different gynecologic malignancies, who were treated with cisplatinum and endoxan. A statistically highly significant decrease was demonstrated 2 h after starting treatment with a further significant decrease at 6 h. After 12 h the erythropoietin concentrations returned to values similar to those before treatment started.
doi_str_mv 10.1007/BF02389607
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subjects Adult
Aged
Antineoplastic Combined Chemotherapy Protocols - adverse effects
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Cisplatin - administration & dosage
Cisplatin - adverse effects
Cyclophosphamide - administration & dosage
Cyclophosphamide - adverse effects
Erythropoietin - blood
Female
Genital Neoplasms, Female - blood
Genital Neoplasms, Female - drug therapy
Humans
Middle Aged
title Influence on erythropoietin levels of treatment with cisplatinum-endoxan
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