On the role of divalent cations in the reaction mechanism of malic enzyme

On the role of divalent cations in the reaction mechanism of malic enzyme

The kinetic order of addition of Mg2+ and L-malate to malic enzyme has been determined. Mg2+ is the first to bind, and probably acts as a link between the substrate and the active site.

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Veröffentlicht in:Experientia 1975-10, Vol.31 (10), p.1126-1128
Hauptverfasser: Massarini, E, Cazzulo, J J
Format: Artikel
Sprache:eng
Schlagworte:
Cations, Divalent
Cobalt - pharmacology
Kinetics
Magnesium - pharmacology
Malate Dehydrogenase - metabolism
Manganese - pharmacology
Pseudomonas - enzymology
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container_title Experientia
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creator Massarini, E
Cazzulo, J J
description The kinetic order of addition of Mg2+ and L-malate to malic enzyme has been determined. Mg2+ is the first to bind, and probably acts as a link between the substrate and the active site.
doi_str_mv 10.1007/BF02326748
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source MEDLINE; SpringerLink Journals - AutoHoldings
subjects Cations, Divalent
Cobalt - pharmacology
Kinetics
Magnesium - pharmacology
Malate Dehydrogenase - metabolism
Manganese - pharmacology
Pseudomonas - enzymology
title On the role of divalent cations in the reaction mechanism of malic enzyme
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