Digoxin toxicity in a premature infant: treatment with Fab fragments of digoxin-specific antibodies
The first use of Fab fragments to treat digoxin toxicity in a premature infant with renal failure, 18 h after the onset of severe arrhythmias, is reported with dramatic results. The development of digoxin toxicity in the context of accepted therapeutic dosing to treat heart failure due to a cerebral...
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| Veröffentlicht in: | Pediatric cardiology 1985-01, Vol.6 (2), p.91-93 |
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| container_end_page | 93 |
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| container_issue | 2 |
| container_start_page | 91 |
| container_title | Pediatric cardiology |
| container_volume | 6 |
| creator | Presti, S Friedman, D Saslow, J Doyle, E F Butler, V P Smith, T W Haber, E |
| description | The first use of Fab fragments to treat digoxin toxicity in a premature infant with renal failure, 18 h after the onset of severe arrhythmias, is reported with dramatic results. The development of digoxin toxicity in the context of accepted therapeutic dosing to treat heart failure due to a cerebral arteriovenous malformation is discussed. |
| doi_str_mv | 10.1007/BF02282744 |
| format | Article |
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The development of digoxin toxicity in the context of accepted therapeutic dosing to treat heart failure due to a cerebral arteriovenous malformation is discussed.</description><subject>Arrhythmias, Cardiac - chemically induced</subject><subject>Arrhythmias, Cardiac - therapy</subject><subject>Digoxin - adverse effects</subject><subject>Digoxin - immunology</subject><subject>Disorders of Sex Development - complications</subject><subject>Humans</subject><subject>Immunoglobulin Fab Fragments - therapeutic use</subject><subject>Infant, Newborn</subject><subject>Infant, Premature, Diseases - chemically induced</subject><subject>Infant, Premature, Diseases - therapy</subject><issn>0172-0643</issn><issn>1432-1971</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM1LAzEQxYMotVYv3oWchdXJx-4m3rRaFQpe9Lxkk0mNuN0lSdH-926p6GVm3vDmMfwIOWdwxQDq67sFcK54LeUBmTIpeMF0zQ7JFFjNC6ikOCYnKX0AgAJVTshEQqmhFlNi78Oq_w5rmsdqQ97ScTZ0iNiZvIk4Sm_W-YbmiCZ3uM70K-R3ujAt9dGsdptEe0_dPqdIA9rgg6XjVWh7FzCdkiNvPhOe_fYZeVs8vM6fiuXL4_P8dlnY8flc1L5kolZKgmTokWtdYlu5qvLKcVTGlgwBtfPotFW2lNqZSlgP3DihPYoZudzn2tinFNE3QwydiduGQbMD1fyDGs0Xe_OwaTt0f9ZfMuIHL8BkyQ</recordid><startdate>19850101</startdate><enddate>19850101</enddate><creator>Presti, S</creator><creator>Friedman, D</creator><creator>Saslow, J</creator><creator>Doyle, E F</creator><creator>Butler, V P</creator><creator>Smith, T W</creator><creator>Haber, E</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19850101</creationdate><title>Digoxin toxicity in a premature infant: treatment with Fab fragments of digoxin-specific antibodies</title><author>Presti, S ; Friedman, D ; Saslow, J ; Doyle, E F ; Butler, V P ; Smith, T W ; Haber, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c282t-7f5137884041efe2995eb6d66f8d2e8ac51e0e9dfed9c8c549da63cf02ad39fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Arrhythmias, Cardiac - chemically induced</topic><topic>Arrhythmias, Cardiac - therapy</topic><topic>Digoxin - adverse effects</topic><topic>Digoxin - immunology</topic><topic>Disorders of Sex Development - complications</topic><topic>Humans</topic><topic>Immunoglobulin Fab Fragments - therapeutic use</topic><topic>Infant, Newborn</topic><topic>Infant, Premature, Diseases - chemically induced</topic><topic>Infant, Premature, Diseases - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Presti, S</creatorcontrib><creatorcontrib>Friedman, D</creatorcontrib><creatorcontrib>Saslow, J</creatorcontrib><creatorcontrib>Doyle, E F</creatorcontrib><creatorcontrib>Butler, V P</creatorcontrib><creatorcontrib>Smith, T W</creatorcontrib><creatorcontrib>Haber, E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Pediatric cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Presti, S</au><au>Friedman, D</au><au>Saslow, J</au><au>Doyle, E F</au><au>Butler, V P</au><au>Smith, T W</au><au>Haber, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Digoxin toxicity in a premature infant: treatment with Fab fragments of digoxin-specific antibodies</atitle><jtitle>Pediatric cardiology</jtitle><addtitle>Pediatr Cardiol</addtitle><date>1985-01-01</date><risdate>1985</risdate><volume>6</volume><issue>2</issue><spage>91</spage><epage>93</epage><pages>91-93</pages><issn>0172-0643</issn><eissn>1432-1971</eissn><abstract>The first use of Fab fragments to treat digoxin toxicity in a premature infant with renal failure, 18 h after the onset of severe arrhythmias, is reported with dramatic results. The development of digoxin toxicity in the context of accepted therapeutic dosing to treat heart failure due to a cerebral arteriovenous malformation is discussed.</abstract><cop>United States</cop><pmid>4059073</pmid><doi>10.1007/BF02282744</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0172-0643 |
| ispartof | Pediatric cardiology, 1985-01, Vol.6 (2), p.91-93 |
| issn | 0172-0643 1432-1971 |
| language | eng |
| recordid | cdi_crossref_primary_10_1007_BF02282744 |
| source | MEDLINE; Springer Journals |
| subjects | Arrhythmias, Cardiac - chemically induced Arrhythmias, Cardiac - therapy Digoxin - adverse effects Digoxin - immunology Disorders of Sex Development - complications Humans Immunoglobulin Fab Fragments - therapeutic use Infant, Newborn Infant, Premature, Diseases - chemically induced Infant, Premature, Diseases - therapy |
| title | Digoxin toxicity in a premature infant: treatment with Fab fragments of digoxin-specific antibodies |
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