Neurogenic and tissue-mediated components of formalin-induced edema: evidence for supraspinal regulation

Injection of formalin into a hind paw of rats produces localized inflammation and pain. The nociceptive effect of formalin, recorded as flinching/shaking of the injected paw, is biphasic. The present study shows that formalin-induced inflammation and edema (assessed by measurement of paw volume up t...

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Veröffentlicht in:Agents and Actions 1991-09, Vol.34 (1-2), p.264-269
Hauptverfasser: Wheeler-Aceto, H, Cowan, A
Format: Artikel
Sprache:eng
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