Autoradiographic analysis of FSH binding during follicular atresia

Binding of FSH to ovarian cells was studied in PMSG primed immature Swiss mice, 48 h after PMSG treatment, FSH-binding was higher in the periphery than in the cumulus cells of the antral follicles. Binding of FSH to granulosa cells of normal follicles was observed to be specific, 48 h after PMSG inj...

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Veröffentlicht in:	Experientia 1983-07, Vol.39 (7), p.792-793
Hauptverfasser:	Balachandran, P K, Moodbidri, S B, Nandedkar, T D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoradiography Binding Sites - drug effects Female Follicle Stimulating Hormone - metabolism Gonadotropins, Equine - pharmacology Iodine Radioisotopes Mice Mice, Inbred Strains Ovarian Follicle - drug effects Ovarian Follicle - metabolism Time Factors
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Beschreibung
Zusammenfassung:	Binding of FSH to ovarian cells was studied in PMSG primed immature Swiss mice, 48 h after PMSG treatment, FSH-binding was higher in the periphery than in the cumulus cells of the antral follicles. Binding of FSH to granulosa cells of normal follicles was observed to be specific, 48 h after PMSG injection. No localization in the atretic follicles could be seen by autoradiography 72 h after priming.
ISSN:	0014-4754 1420-9071
DOI:	10.1007/BF01990331