Proteins in the plasma membranes of rat peritoneal mast cells

Plasma membranes of peritoneal mast cells from rats specifically bred for resistance to the dextran anaphylactoid reaction contain a polypeptide of molecular weight about 74,000 daltons which is deficient in those from rats which react to dextran. This polypeptide may modify the dextran receptor on...

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Veröffentlicht in:	Agents and Actions 1983-04, Vol.13 (2-3), p.141-143
Hauptverfasser:	Ludowyke, R I, West, G B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ascitic Fluid - cytology Cell Membrane - analysis Dextrans - pharmacology Histamine Release - drug effects In Vitro Techniques Male Mast Cells - analysis Membrane Proteins - analysis Molecular Weight Rats Rats, Inbred Strains
Online-Zugang:	Volltext
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Zusammenfassung:	Plasma membranes of peritoneal mast cells from rats specifically bred for resistance to the dextran anaphylactoid reaction contain a polypeptide of molecular weight about 74,000 daltons which is deficient in those from rats which react to dextran. This polypeptide may modify the dextran receptor on the mast cell membranes of resistant rats so that histamine release does not take place when these cells are challenged with clinical dextran.
ISSN:	0065-4299 1420-908X
DOI:	10.1007/BF01967318