The correlation between allergen, acetylcholine and histamine-induced bronchoconstriction

The correlation between allergen, acetylcholine and histamine-induced bronchoconstriction

A significant correlation between the degree of bronchial reactivity to ACH, Hi and A.E. was found in a series of 23 dogs. An increase in receptors sensitivity responsible for the organic manifestation of allergy must be assumed. This increased receptors sensitivity is an important phenomenon in ast...

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Veröffentlicht in:Agents and Actions 1984-12, Vol.15 (5-6), p.474-477
Hauptverfasser: Zimmermann, I, Bugalho de Almeida, A A, Ulmer, W T
Format: Artikel
Sprache:eng
Schlagworte:
Acetylcholine - pharmacology
Allergens - pharmacology
Animals
Bronchi - drug effects
Bronchi - physiology
Dogs
Female
Histamine - pharmacology
Male
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Zusammenfassung:A significant correlation between the degree of bronchial reactivity to ACH, Hi and A.E. was found in a series of 23 dogs. An increase in receptors sensitivity responsible for the organic manifestation of allergy must be assumed. This increased receptors sensitivity is an important phenomenon in asthma clinically relevant.
ISSN:0065-4299
1420-908X
DOI:10.1007/BF01966758