Alterations in bone-marrow cellularity following thymectomy in rats

Alterations in bone-marrow cellularity following thymectomy in rats

The number of nucleated marrow cells was decreased following neonatal thymectomy in rats, and was corrected by administration of syngeneic lymphoid cells, or by implantation of a syngeneic testis. These results suggest that, in the rat, as has been shown previously in the mouse, lymphoid cells exert...

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Veröffentlicht in:Experientia 1979-10, Vol.35 (10), p.1401-1402
Hauptverfasser: Lipscomb, H L, Sharp, J G
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Animals, Newborn
Bone Marrow Cells
Female
Male
Rats
Testis - transplantation
Thymectomy
Transplantation, Isogeneic
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Zusammenfassung:The number of nucleated marrow cells was decreased following neonatal thymectomy in rats, and was corrected by administration of syngeneic lymphoid cells, or by implantation of a syngeneic testis. These results suggest that, in the rat, as has been shown previously in the mouse, lymphoid cells exert parital control over bone marrow cellularity and this effect may be further modulated by sex steroids.
ISSN:0014-4754
1420-9071
DOI:10.1007/BF01964034